33770040永利

博士/副教授

TEL/ 0635-8230195

EMAIL/ lixia@lcu.edu.cn

科研方向/分析化学

• 讲授课程：《化学前沿》、《分析化学实验》、《仪器分析实验》、《物理化学实验》、《无机及分析化学实验》

• 教育经历：2006. 6 33770040永利 33770040永利  化学教育 本科

           2009.6  长春理工大学    应用化学     硕士

        2013.7 中科院长春应用化学研究所 分析化学 博士

       2011.1-2012.7  香港大学  化学系    研究员助理

       2015. 4-2019.4 山东大学 33770040永利 分析化学 博后

       2021.8-2022.8  中科院上海应用物理研究所   访问学者

• 科研项目：(1）山东省自然科学面上基金，资助额度，20万（主持）；                           （2）山东高等学校科技计划重点项目，资助额度，10万 （主持）；

• 获奖情况（1）山东省高等学校科学技术二等奖；（2）“山东省优秀硕士学位论文”指导教师；（3）“山东省研究生优秀成果三等奖”指导教师  

• 论著一览 代表性文章 [1] Xia Li, Liqi Liu, Fei Yin, Yeling Liu, Shuling Xu, Wei Jiang*, Rui Wang, Qingwang Xue*. In situ generation spatial confinement fluorescence RNA for sensitive and stable imaging of telomerase RNA in cells. Sens. Actuators B Chem., 2021, 345, 130414.

[2]    Li-qi Liu, Fei Yin, Yu Lu, Xi-luan Yan, Ching-Chou Wu, Xia Li*, Chenzhong Li*. A light-up “G-quadruplex Nanostring” for label-free and selective detection of miRNA via duplex-specific nuclease mediated tandem rolling circle amplification. Nanomed. Nanotech. Biol. Med. 2021, 32, 102339.

[3]    Yeling Liu, Xia Sun, Hui Yuan, Bingxin Liu, Xueing Chen, Xia Li*, Qingwang Xue*. Sensitive detection of p53 DNA based on spatially confined fluorescence resonance energy transfer and multivalent assembly of branched DNA. Anal. Methods, 2021, 13, 4314.

[4] Xia Sun, Yeling Liu, Liqi Liu, Fei Yin, Ruixin Liu, Tianyu Guo, Xia Li*, and Qingwang Xue. Label-free amplified fluorescence detection of DNA biomarkers based on KFP polymerase-driven double strand displacement reactions and magnetic nanoprobes. Anal. Methods, 2020, 12, 3092. (封面）

[5] Xia Li, Fei Yin, Xiaowen Xu, LiqiLiu, Qingwang Xue, LinTong, Wei Jiang*, Chen-zhong Li*. A facile DNA/RNA nanoflower for sensitive imaging of telomerase RNA in living cells based on “zipper lock-and-key” strategy. Biosens. Bioelectron., 2020, 147, 111788.

[6] Fei Yin, Liqi Liu, Xia Sun, Laiyong Hou, Yu Lu, Qingwang Xue, Tong Lin, Xia Li*, and Chen-zhong Li*. A facile deoxyuridine /biotin-modified molecular beacon for simultaneous detection of proteins and nucleic acids via a label-free and background-eliminated fluorescence assay. Analyst, 2019, 142, 3598.

[7] Xia Li, Xiaowen Xu, Juan Song, Qingwang Xue, Chen-zhong Li*, Wei Jiang*. Sensitive detection of T4 polynucleotide kinase activity based on multifunctional magnetic probes and polymerization nicking reactions mediated hyperbranched rolling circle amplification. Biosens. Bioelectron., 2017, 91, 631.

[8] Xia Li, Juan Song, Qingwang Xue, Haiyan Zhao, Min Liu, Baoli Chen, Yun Liu, Wei Jiang*, Chen-zhong Li*. Sensitive and selective detection of the p53 gene based on a triple-helix magnetic probe coupled to a ?uorescent liposome hybridization assembly via rolling circle ampli?cation. Analyst, 2017, 142, 3598.

[9] Xia Li, Juan Song, Qingwang Xue, Fuheng You, Xia Lu, Yancong Kong, Shuyi Ma, Wei Jiang*, Chen-zhong Li*. A label-free and sensitive fluorescent qualitative assay for bisphenol A based on rolling circle amplification/exonuclease III-combined cascade amplification. Nanomaterials, 2016, 6, 190.

[10] Xia Li, Juan Song, Baoli Chen, Bing Wang, Rui Li, Huimin Jiang, Jifeng Liu*, Chen-zhong Li*. A label-free colorimetric assay for detection of c-Myc mRNA based on peptide nucleic acid and silver nanoparticles. Sci. Bull, 2016, 61(4), 276.

• 相关成果  （1）研究生培养：2019年 获山东省优秀硕士学位论文；2020年获“山东省研究生优秀成果三等奖”； 研究生获得校级奖学金 一等奖 3人次，二等奖4人次；目前已有三名研究生分别考取南京大学、东南大学和江苏大学博士；

（2）本科生培养：本科生署名发表SCI论文约15人次，协助本科生申请国家级大学生创新创业项目3项，校级创新创业项目5项目。